Knee osteoarthritis doesn’t happen overnight—it progresses silently through four stages, each with its own characteristics and recommended treatment approach.
In Stage 1, the joint space appears almost normal, with only minor bone spurs beginning to form. Most patients experience no symptoms, except occasional discomfort after intense physical activity. At this point, adopting healthy lifestyle habits and providing proper joint nutrition are essential.
By Stage 2, the joint space begins to narrow slightly, and mild pain or stiffness may occur during movement or in cold weather. This is an ideal time to intervene with gentle exercise, weight management, and possibly intra-articular Hyaluronic Acid (HA) injections to help lubricate and protect the joint cartilage.
In Stage 3, the condition becomes more serious. The joint space narrows significantly, cartilage damage worsens, and bone spurs are more prominent. Patients often experience persistent pain, morning stiffness, and even joint effusion. Treatment at this stage typically includes a combination of medication, physical therapy, and more advanced interventions like HA injections or arthroscopic surgery.

By Stage 4, the joint is severely deformed, and bone-on-bone contact causes intense pain. Joint fusion, inflammation, and visible deformities are common. At this point, knee replacement surgery may be necessary to restore mobility and improve quality of life.
While knee osteoarthritis is not life-threatening, it can gradually erode your quality of life. Early detection and timely treatment are key to preventing long-term complications. Don’t ignore ongoing knee pain—listen to your body and seek medical advice as soon as symptoms appear.
RegenoGel is an innovative treatment option that supports joint recovery by stimulating the body’s natural production of Hyaluronic Acid, promoting sustainable improvement in joint function and mobility.